Clinical case: PET/CT imaging helps in detecting small nodules

Detecting Small Nodules

Who we are


Doctor Candela Bartolomeo
Chief of the Nuclear Medicine Department

Villa Santa Teresa, Medicina Nucleare San Gaetano, Bagheria (Palermo), Italy

Patient History

Female - 42 years old - 170 cm - 65 kg.

Several imaging tests including mammography and ultrasound failed to identify the primary tumor.


Scanner: GE Discovery ST

PET acquisition: Whole-body acquisition

  • 3D acquisition using VUE Point HD reconstruction –256 x 256 matrix
  • Acquisition time: 3 min/bed
  • Post-injection time: 50 min
  • Dose: 319 MBq of 18F-FDG

CT acquisition: CT Attenuation Correction

  • Whole-body acquisition
  • Smart mA
  • Auto mA: min 30 - Max 130mA - NI 30



                      Whole-body static image –
                      Highlight of hypermetabolic
                      lesions in the left breast


CT and fused coronal views of the breast hypermetabolic lesion


CT and fused axial views of a small hypermetabolic internal mammary node

Multiple hypermetabolic uptakes of 18F-FDG in the right and left axillar
nodes, right cervical nodes and internal mammary nodes involvment.

Single area of hypermetabolic uptake of 18F-FDG in the
inner lower lateral left breast.


Patient with palpable lymph nodes in the left and right axilla.

18F-FDG PET identified a hypermetabolic lesion in the breast.